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IIR document

Noble gas isotopes as biomarkers.

Number: pap. n. 45

Author(s) : ARKHAROV I., NAVASARDYAN E., DOLGOPYATOV D.

Summary

The details of production of a new type of biomarkers for the magnetic resonance imaging (MRI) based on stable isotopes of noble gases are examined. The state-of-the-art cryogenic technology provides means to enrich and produce stable isotopes of neon 20Ne, 21Ne, xenon 129Xe, 136Xe and helium 3He on an industrial scale. In particular, a cryogenic distillation at 28 K is used to produce 20Ne concentrated distillate and to extract 22Ne isotope. A cascade arrangement of distillation columns enables 99.95% isotope concentrated and 99.999% product purity. In this connection, a new trend of such isotopes application as hyperpolarized gas biomarkers for noninvasive reusable MRI diagnostics of lungs, brain, cardiovascular and lymphatic systems, affording multiple repetitions in a short period of time, is particularly interesting.

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Pages: 5 p.

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Details

  • Original title: Noble gas isotopes as biomarkers.
  • Record ID : 30011150
  • Languages: English
  • Source: Cryogenics 2014. Proceedings of the 13th IIR International Conference: Prague, Czech Republic, April 7-11, 2014.
  • Publication date: 2014/04/07

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