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AN INVESTIGATION OF THE HISTOPATHOLOGICAL AND ENZYME HISTOCHEMICAL CHANGES OF JAPANESE WHITE RABBIT SKIN FROZEN WITH LIQUID NITROGEN.

Author(s) : FENG S., XIAO B., LI Q.

Summary

THE EXPERIMENT SUGGESTS THAT CELL DAMAGE AND DEATH IN THE FREEZING PROCESS IS CAUSED MAINLY BY DEHYDRATION ; CELLULAR MEMBRANE STRUCTURE INJURIES AND INFILTRATION CHANGES ARE MAIN FACTORS. THUS, THE CRYOTHERAPY METHOD IN CLINICAL WORK SHOULD ADAPT THE COOLING SPEED OF CELLS, SO AS TO KEEP THE CELLS UNDER SUPERFREEZING FOR A LONG TIME. THE METHOD OF REPEATED THAWING CAUSES SERIOUS CELL DEHYDRATION WITH LETHAL CELLULAR INJURIES AND DEATH.

Details

  • Original title: AN INVESTIGATION OF THE HISTOPATHOLOGICAL AND ENZYME HISTOCHEMICAL CHANGES OF JAPANESE WHITE RABBIT SKIN FROZEN WITH LIQUID NITROGEN.
  • Record ID : 1990-2597
  • Languages: English
  • Publication date: 1989/10/11
  • Source: Source: Proc. 7th int. Congr. Cryosurg., Beijing
    99-106; 12 fig.; 12 ref.
  • Document available for consultation in the library of the IIR headquarters only.

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