FUNCTIONAL CHANGES IN MITOCHONDRIAL PROPERTIES AS A RESULT OF THEIR MEMBRANE CRYODESTRUCTION. II. INFLUENCE OF FREEZING AND THAWING ON ATP COMPLEX ACTIVITY OF INTACT LIVER MITOCHONDRIA.

Type of article: Article

Summary

THE INFLUENCE OF THE FREEZE-THAWING RATES ON ATP SYNTHETASE (ATPASE) COMPLEX OF INTACT LIVER MITOCHONDRIA WAS INVESTIGATED. AN INCREASE IN FREEZE-THAWING RATES LED TO THE PRESERVATION OF ATPASE ACTIVITY AND ATP HYDROLYSIS REDUCTION. KINETIC PARAMETER CHANGES OF THE ATPASE REACTION RESULTED FROM AN INSIGNIFICANT NONSPECIFIC INCREASE IN THE INNER MITOCHONDRIAL MEMBRANE PERMEABILITY AND CHANGES IN ITS ELECTROCHEMICAL POTENTIAL LEVEL.

Details

Original title: FUNCTIONAL CHANGES IN MITOCHONDRIAL PROPERTIES AS A RESULT OF THEIR MEMBRANE CRYODESTRUCTION. II. INFLUENCE OF FREEZING AND THAWING ON ATP COMPLEX ACTIVITY OF INTACT LIVER MITOCHONDRIA.
Record ID : 1985-2682
Languages: English
Source: Cryobiology - vol. 22 - n. 2
Publication date: 1985

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Themes: The influence of refrigeration on cells, tissues and organs
Keywords: Thawing rate; Cell; Freezing rate; Mitochondria; Membrane; Enzyme; Cryopreservation; Liver