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Inhibition of biotransformation of xenobiotic p-nitroanisole after cryopreservation of isolated rat hepatocytes.

Author(s) : PETRENKO A. Ju., MAZUR S. P.

Type of article: Article

Summary

Decrease of rat hepatocyte metabolism after cryopreservation was investigated. The presence of cryoprotectants allows significant but reduced preservation of studied xenobiotic p-nitroanisole metabolism. The data indicate that this decrease results from the loss of pyridine nucleotide due to the damage of plasma membrane.

Details

  • Original title: Inhibition of biotransformation of xenobiotic p-nitroanisole after cryopreservation of isolated rat hepatocytes.
  • Record ID : 1994-1886
  • Languages: English
  • Source: Cryobiology - vol. 30 - n. 2
  • Publication date: 1993/04

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