Partager

Accumulation de dégâts majeurs dans le foie de lapin surgelé, provoqués par des efforts mécaniques à températures cryogéniques.

Gross damage accumulation in frozen rabbit liver due to mechanical stress at cryogenic temperatures.

Auteurs : RABIN Y., OLSON P., TAYLOR M. J., STEIF P. S., JULIAN T. B., WOLMARK N.

Type d'article : Article

Résumé

No significant gross histological damage was observed in the liver samples due to either processing the tissue in the frozen state, due to slow cooling of the liver tissues down to -20 deg C, or due to rapid cooling of the samples down to -196 deg C. No histological changes were observed in tissue samples that were loaded within the elastic regime that is, below the yield strength of the material. Histological observations indicate that linear cracks which appear to have no preferred orientation develop due to mechanical stress beyond the yield strength of the frozen tissue. These cracks accumulate until final failure of the frozen tissue, when the tissue sample collapses to rubble. Based on histological observations and concepts from solid mechanics, an interaction between crack formation and irregularities in the frozen medium is suggested. Significant sources for such irregularities, in an homogeneous tissue such as the liver, are blood vessels and bile ducts. These irregularities may either initiate crack formation or, on the other hand, may also arrest propagating cracks.

Détails

  • Titre original : Gross damage accumulation in frozen rabbit liver due to mechanical stress at cryogenic temperatures.
  • Identifiant de la fiche : 1998-1964
  • Langues : Anglais
  • Source : Cryobiology - vol. 34 - n. 4
  • Date d'édition : 06/1997

Liens


Voir d'autres articles du même numéro (8)
Voir la source

Indexation