Effet magnétocalorique appliqué au traitement d'une tumeur cancéreuse : méthode d'hyperthermie améliorée.

Efecto magnetocalórico aplicado para destruir un tumor cancerígeno: un método mejorado de hipertermia.

Auteurs : ZATSEPINA E., TISHIN A., EGOLF P. W., et al.

Type d'article : Article

Résumé

In this study, Gd and the alloy Fe(49)Rh(51) are considered to be possible magnetocaloric materials for a new hyperthermia method. From general principles of thermodynamics a new mathematical model allowing the calculation of heat transport in a tumour was developed and numerical simulations were performed. The heating-up time as a dependence of the size and mass of a spherical tumour is determined. Estimates of the necessary frequency in dependence of the particle concentration and temperature are presented. In the case of Gd nanoparticles, approximate and accurate calculations are made by assuming that the covering material of the particles consist of poly(N-isopropylacrylamide) hydrogel. Dynamic heat transfer processes are graphically visualized.

Documents disponibles

Format PDF

Pages : 17-25 (8 p.)

Disponible

  • Prix public

    20 €

  • Prix membre*

    15 €

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