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Pressurisation des salles propres pharmaceutiques.

Pressurisation of pharmaceutical cleanrooms.

Auteurs : BALIGA B. G.

Type d'article : Article

Résumé

Cleanroom spaces are maintained with pressure differentials between rooms as an important tool to achieve contamination control. By maintaining the room at a higher pressure, the products can be protected from contaminants from the adjoining spaces. On the other hand, potent products like penicillin and nuclear medicines can be kept in containment by maintaining the room at a lower pressure. Maintaining the required pressure gradient and ensuring that there are no airflow reversals pose peculiar challenges. Movement of personnel and materials between rooms involving opening and closing of doors, changing gaps between doors and frames due to wearing of gaskets and changing supply air, return air and exhaust air quantities are some of the variables which disturb the pressure differentials all the time. This article discusses the means to achieve and control the room pressure differentials for pharmaceutical cleanrooms and also indicates the energy consumed to maintain pressure gradient.

Documents disponibles

Format PDF

Pages : 62-70 (6 p.)

Disponible

  • Prix public

    20 €

  • Prix membre*

    15 €

* meilleur tarif applicable selon le type d'adhésion (voir le détail des avantages des adhésions individuelles et collectives)

Détails

  • Titre original : Pressurisation of pharmaceutical cleanrooms.
  • Identifiant de la fiche : 30011551
  • Langues : Anglais
  • Source : Air Conditioning and Refrigeration Journal - vol. 17 - n. 2
  • Date d'édition : 03/2014

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