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Effet des taux de variation de la température sur la durée de vie des appareils thermoélectriques dans les instruments d’amplification en chaîne par polymérase (PCR).

Effect of temperature variation rate on the life of thermoelectric devices in PCR instruments.

Numéro : 0001

Auteurs : YAN J., LIU Z., SHEN L., XIE J.

Résumé

Polymerase chain reaction (PCR) is an in vitro molecular cloning technology that is widely used in medical testing, agricultural development and industrial pharmaceuticals. At present, PCR machines mainly use TEC for rapid heating and cooling to create temperature cycles. However, the cycle conditions will cause structural damage and significant performance degradation, causing device failure. This paper proposes a thermoelectric device performance degradation and life prediction model. After verifying the accuracy of the model, the impact of different temperature change rates on the device life is studied. When the average temperature change rate is 2.5℃/s, the lifespan of the device is approximately 28.27 years; when the average temperature change rate is 5℃/s, the lifespan will be dropped to 25.70 years. This article has positive significance for promoting the use of thermoelectric devices and the selection of temperature change rates of traditional PCR instruments.

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Pages : 8

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Détails

  • Titre original : Effect of temperature variation rate on the life of thermoelectric devices in PCR instruments.
  • Identifiant de la fiche : 30032609
  • Langues : Anglais
  • Sujet : Technologie
  • Source : 10th IIR Conference on Caloric Cooling and Applications of Caloric Materials
  • Date d'édition : 24/08/2024
  • DOI : http://dx.doi.org/10.18462/iif.thermag.2024.001

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