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L'ajout d'agents anticancéreux améliore la destruction provoquée par la congélation des cellules cancéreuses de la prostate : implications du rôle des mitochondries.

Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement.

Auteurs : CLARKE D. M., BAUST J. M., BUSKIRK R. G. van, et al.

Type d'article : Article

Résumé

Recent evidence suggests that the successful treatment of prostate cancer may require adjuvant therapies. Accordingly, a better understanding of the molecular mechanisms involved in current treatments may lead to enhanced efficacy by providing a basis for adjuvant therapies. In this study, the authors demonstrate that the combination of sub-lethal concentrations of chemotherapeutic agents prior to freezing (-15 °C) in a prostate cancer cell (PC-3) model results in enhanced efficacy over either treatment alone.

Détails

  • Titre original : Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement.
  • Identifiant de la fiche : 2005-0987
  • Langues : Anglais
  • Source : Cryobiology - vol. 49 - n. 1
  • Date d'édition : 12/2004

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