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Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement.

Author(s) : CLARKE D. M., BAUST J. M., BUSKIRK R. G. van, et al.

Type of article: Article

Summary

Recent evidence suggests that the successful treatment of prostate cancer may require adjuvant therapies. Accordingly, a better understanding of the molecular mechanisms involved in current treatments may lead to enhanced efficacy by providing a basis for adjuvant therapies. In this study, the authors demonstrate that the combination of sub-lethal concentrations of chemotherapeutic agents prior to freezing (-15 °C) in a prostate cancer cell (PC-3) model results in enhanced efficacy over either treatment alone.

Details

  • Original title: Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement.
  • Record ID : 2005-0987
  • Languages: English
  • Source: Cryobiology - vol. 49 - n. 1
  • Publication date: 2004/12

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