Les sucres exercent une grande influence sur les propriétés de vitrification de solutions à base d'éthylène glycol et sont faiblement toxiques pour les embryons et les ovocytes.

Sugars exert a major influence on the vitrification properties of ethylene glycol-based solutions and have low toxicity to embryos and oocytes.

Auteurs : KULESHOVA L. L., MACFARLANE D. R., TROUNSON A. O., et al.

Type d'article : Article

Résumé

A systematic approach was used to assess the vitrification properties of ethylene glycol-based solutions supplemented with carbohydrates. Solutions were prepared using ethylene glycol as the cryoprotectant, 0.9% sodium chloride in water, and six different sugars: D-glucose, D(-)-fructose, D-sorbitol, sucrose, D(+)-trehalose, and raffinose. The authors conclude that added sugars do contribute to a solution's overall vitrification properties, and their properties should be taken into consideration when vitrification solutions are being designed or modified.

Détails

  • Titre original : Sugars exert a major influence on the vitrification properties of ethylene glycol-based solutions and have low toxicity to embryos and oocytes.
  • Identifiant de la fiche : 2000-1024
  • Langues : Anglais
  • Source : Cryobiology - vol. 38 - n. 2
  • Date d'édition : 03/1999

Liens


Voir d'autres articles du même numéro (6)
Voir la source