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Effet bénéfique de la tréhalose intracellulaire sur la viabilité des globules rouges lyophilisés.

[In Chinese. / En chinois.]

Auteurs : HE H., LIU B. L., HUA Z. H., et al.

Type d'article : Article

Résumé

Currently, freeze-drying is one of the best methods for the preservation of red blood cells. The effects of intracellular trehalose on the viability of freeze-dried red blood cells were investigated. The fresh red blood cells were incubated in trehalose solutions of various concentrations at 37°C for 7 hours. The results show that the intracellular trehalose concentration increased with the increasing concentration of extracellular trehalose solution. The maximum concentration of intracellular trehalose was 35 mmol/L in the study. Red blood cells loaded with trehalose were lyophilized with the concentrations of trehalose of 15, 22.5, 30 and 37.5% respectively. The results show that the viability of freeze-dried red blood cells increased with the increase of intracellular trehalose concentration.

Documents disponibles

Format PDF

Pages : 41-44

Disponible

  • Prix public

    20 €

  • Prix membre*

    15 €

* meilleur tarif applicable selon le type d'adhésion (voir le détail des avantages des adhésions individuelles et collectives)

Détails

  • Titre original : [In Chinese. / En chinois.]
  • Identifiant de la fiche : 2006-3218
  • Langues : Chinois
  • Source : Journal of Refrigeration - vol. 27 - n. 109
  • Date d'édition : 06/2006

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