Partager

Document IIF

Transport couplé d'eau et d'agent cryoprotecteur à travers des membranes cellulaires et applications à la cryoconservation.

Coupled transport of water and cryoprotectant across cell membranes and applications to cryopreservation.

Numéro : pap. n. 003

Auteurs : WENG L., LI W.

Résumé

The field of cryobiology has progressed as a fertile ground for new discoveries with important applications in cryopreservation over the past several decades. Some well-known thermodynamic models were proposed to predict the biophysical response of living cells and tissues in cryopreservation. This study, for the first time, develops a model that can calculate the coupled transport of water and cryoprotectants across cell membranes during the freezing and thawing protocols. The new model can eradicate the long-standing contradiction between the conventional Mazur model and the modern 2-P or K-K one. For cryobiological practice, the new model is applied to predict the volumetric change for human corneal keratocytes in the freezing protocol. The findings in this study will offer new insights into the biophysical response of biomaterials experiencing cryopreservation procedures.

Documents disponibles

Format PDF

Pages : 246-251

Disponible

  • Prix public

    20 €

  • Prix membre*

    Gratuit

* meilleur tarif applicable selon le type d'adhésion (voir le détail des avantages des adhésions individuelles et collectives)

Détails

  • Titre original : Coupled transport of water and cryoprotectant across cell membranes and applications to cryopreservation.
  • Identifiant de la fiche : 30006655
  • Langues : Anglais
  • Source : Cryogenics 2012. Proceedings of the 12th IIR International Conference: Dresden, Germany, September 11-14, 2012.
  • Date d'édition : 11/09/2012

Liens


Voir d'autres communications du même compte rendu (78)
Voir le compte rendu de la conférence

Indexation