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Membranes plaquettaires : altérations dues au refroidissement et à la congélation.

Cooling and freezing damage platelet membrane integrity.

Auteurs : REID T. J., LARUSSA V. F., ESTEBAN G., et al.

Résumé

This study investigated the interaction between the platelet cytoskeleton and membrane during storage at 4 °C for 1-21 days, using EGTA/AM and cytochalasin B as platelet protectants. Treated platelets showed a gradual loss of membrane integrity reaching a maximum at 7 days. Untreated platelets had complete loss of integrity and function after 1 day of storage.

Détails

  • Titre original : Cooling and freezing damage platelet membrane integrity.
  • Identifiant de la fiche : 2000-2803
  • Langues : Anglais
  • Date d'édition : 05/1999
  • Source : Source : Cryobiology/Soc. Cryobiol., Annu. Meet., Pittsburgh/Symp. Cryopreserv. human Platelets, Pittsburgh
    vol. 38; n. 3; 209-224; 7 fig.; 1 tabl.; 10 ref.

Indexation