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Etudes sur les altérations structurelles et fonctionnelles de certaines protéines à la suite d'une exposition aux basses températures.

A study of structural and functional state modification of certain proteins when exposed to low temperatures.

Auteurs : NARDID O. A., DYUBCO T. S., ROZANOVA E. D., et al.

Type d'article : Article

Résumé

Rapid freeze-thawing influence on structural state and enzymatic activity of bovine heart cytochrome-C-oxidase, cytochrome P-450 from rabbit liver microsomes and myosin from rabbit muscle was investigated. It was shown that used cryogenic action regimes lead to protein conformational changes, affecting the active center areas as well as peripheral polypeptide chains. At the same time, enzymatic activity of proteins does not change significantly. It was assumed that conformational changes discovered might be non-restrictive as to the studied protein functions.

Détails

  • Titre original : A study of structural and functional state modification of certain proteins when exposed to low temperatures.
  • Identifiant de la fiche : 2000-2567
  • Langues : Anglais
  • Source : Cryo-Letters - vol. 20 - n. 5
  • Date d'édition : 09/1999
  • Document disponible en consultation à la bibliothèque du siège de l'IIF uniquement.

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