L'évolution d'une glycoprotéine antigel.

Evolution of an antifreeze glycoprotein.

Auteurs : CHENG C. H., CHEN L.

Type d'article : Article

Résumé

The ice-binding anti-freeze glycoprotein (AFGP) that circulates in the blood of Antarctic notothenioid fishes enables them to avoid freezing in their perpetually icy environment. This crucial survival protein probably arose from a functionally unrelated pancreatic trypsinogen-like protease. The authors have discovered an important intermediate in this evolutionary process: transcriptionally active chimaeric genes that encode both an AFGP polyprotein and the protease, confirming the protease origin of AFGP and indicating how it was created.

Détails

  • Titre original : Evolution of an antifreeze glycoprotein.
  • Identifiant de la fiche : 2000-0437
  • Langues : Anglais
  • Source : Nature - vol. 401 - n. 6752
  • Date d'édition : 30/09/1999
  • Document disponible en consultation à la bibliothèque du siège de l'IIF uniquement.

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