IIR document

FREEZE-DRYING OF BLOOD PRODUCTS IN THE BLOOD TRANSFUSION SERVICE OF THE GERMAN DEMOCRATIC REPUBLIC.

Author(s) : TOURSEL W., HINDORF H.

Summary

THE BLOOD COMPONENT PRODUCTION IN THE TRANSFUSION STATIONS IS CONNECTED WITH A SPECIFIC REFRIGERATION STORAGE SYSTEM OF DIFFERENT BLOOD PRODUCTS LIKE RED CELL CONCENTRATES, STORED AT 277 K (4 DEG C) FOR A SHORT TIME. ERYTHROCYTES ARE FROZEN AT 245 K (-28 DEG C) FOR 12 MONTHS, OR STORED BY LOW-TEMPERATURE PRESERVATION WITH LN2 FOR MANY YEARS. IN CONTRAST TO THE CELLULAR PART OF BLOOD, THE BLOOD PLASMA AND ISOLATED PLASMATIC SUBSTANCES ARE FREEZE-DRIED. THE MAIN ADVANTAGE OF DRIED PLASMA IS THE STORAGE POSSIBILITY AT ROOM TEMPERATURE UP TO 5 YEARS, BUT ITS DISADVANTAGE IS THE LOSS OF IMPORTANT CLOTTING FACTORS.

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Details

  • Original title: FREEZE-DRYING OF BLOOD PRODUCTS IN THE BLOOD TRANSFUSION SERVICE OF THE GERMAN DEMOCRATIC REPUBLIC.
  • Record ID : 1987-1214
  • Languages: English
  • Source: Fundamentals and Applications of Freeze-Drying to Biological Materials, Drugs and Foodstuffs.
  • Publication date: 1985/05/20
  • Document available for consultation in the library of the IIR headquarters only.

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