ON THE MECHANISM OF THE FREEZE-INDUCED CONDUCTION BLOCK OF ACTION POTENTIALS IN RAT CARDIAC MUSCLE.
Author(s) : BERGER W. K., TOVAR O.
Type of article: Article
Summary
THE FREEZE-INDUCED CONDUCTION BLOCK OF ACTION POTENTIALS OF RAT HEART IS APPARENTLY CAUSED BY A LOSS OF ELECTRICAL MEMBRANE POLARIZATION. BECAUSE THE MEMBRANE OF MANY FROZEN-THAWED CELLS WAS PRESERVED, IT IS SUGGESTED, THAT THE MAJORITY OF THE CELLS WERE NOT DEPOLARIZED BY AN EXCHANGE OF INTRA-AND EXTRA-CELLULAR IONS THROUGH MEMBRANE LESIONS, BUT THROUGH UNCLOSED NEXUS-CHANNELS BETWEEN INJURED AND NON-INJURED CELLS.
Details
- Original title: ON THE MECHANISM OF THE FREEZE-INDUCED CONDUCTION BLOCK OF ACTION POTENTIALS IN RAT CARDIAC MUSCLE.
- Record ID : 1991-0419
- Languages: English
- Source: Cryo-Letters - vol. 11 - n. 1
- Publication date: 1990/01
- Document available for consultation in the library of the IIR headquarters only.
Links
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Indexing
- Themes: The influence of refrigeration on cells, tissues and organs
- Keywords: Cell; Rat; Membrane; Cryopreservation; Heart
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