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THE STABILITY OF THE ROMANIAN FREEZE-DRIED BCG VACCINE.

Author(s) : BALAZS D., PITUR I., DRAGHICI D.

Type of article: Article

Summary

THE SURVIVAL RATES AFTER 12 MONTHS (60 -100% FOR 74% OF BATCHES) OF STORAGE UNDER PROPER CONDITIONS ARE CONSIDERED AS SATISFACTORY ESPECIALLY TAKING INTO ACCOUNT THE DIFFICULTIES TO OBTAIN SIMILAR DATA IN TESTS PERFORMED ON THE SAME BATCH BUT ON DIFFERENT DAYS. THE ACCELERATED DEGRADATION TEST (28 DAYS EXPOSURE AT 37 DEG C) PROVED AN ADEQUATE STABILITY: SURVIVAL RATES BETWEEN 40 AND 55% FOR 83% OF BATCHES. LONG EXPOSURE AT 22 TO 25 DEG C IS AS DELETERIOUS AS THE EXPOSURE FOR 7 DAYS TO 310 K AND SHOULD BE AVOIDED.

Details

  • Original title: THE STABILITY OF THE ROMANIAN FREEZE-DRIED BCG VACCINE.
  • Record ID : 1983-1204
  • Languages: English
  • Source: Arch. roum. Pathol. exp. Microbiol. - vol. 41 - n. 2
  • Publication date: 1982/04
  • Document available for consultation in the library of the IIR headquarters only.

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