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Recommended by the IIR / IIR document

Vaccine cold-chain challenges for fast-track mass COVID-19 vaccination in Bangladesh.

• Author(s) : MUNSHI F., DEBNATH S., SENAN A., PETERS T., GREENING P., WANG X.
• Publication date: 2022/04/11
• Languages : English
• Keywords : Vaccine, COVID-19, Bangladesh, Cold chain, Survey
• Source: 7^th IIR International Conference on Sustainability and the Cold Chain (Online). Proceedings: April 11-13 2022
• Formats : PDF

Vacciner les enfants au-delà de la "chaine de froid" : pour des vaccins moins sensibles à la chaleur.

Vaccinating children beyond the cold chain: towards less heat-sensitive vaccines.

• Publication date: 2014/04
• Languages : French
• Keywords : Vaccine, Heat, Controlled atmosphere, Cold chain, Transport, Quality, Developing country, Distribution

Recommended by the IIR / IIR document

Cold Chain Technology Brief: Vaccines.

• Author(s) : CAVALIER G., FERTEL C., PAOLI F. de, DEVIN E., GOBINA I., ELTALOUNY A., FENNER A. M., MARTIAL J. P.
• Publication date: 2021/09
• Languages : French, English, Spanish
• Keywords : Vaccine, Virus, Cold chain, Temperature, Logistics, Review, COVID-19
• Formats : PDF

Explorative Supercooling Technology for Prevention of Freeze Damages in Vaccines.

• Author(s) : JUN S., KO Y., LEE S. H.
• Publication date: 2022/03
• Languages : English
• Keywords : Supercooling, Design, Vaccine, Temperature, Temperature variation, Magnetic field, Cold chain, Testing
• Source: Applied Sciences - vol. 12 - n. 6
• Formats : PDF

IIR document

Cost effective storage and distribution of temperature sensitive vaccine.

• Author(s) : PEDOLSKY H., CAVALIER G., FERTEL C.
• Publication date: 2023/08/21
• Languages : English
• Keywords : Cold store, Regulations, Vaccine, R290, R170, Propane, Ethane, Low temperature, Freezer, COVID-19
• Source: Proceedings of the 26^th IIR International Congress of Refrigeration: Paris , France, August 21-25, 2023.
• Formats : PDF

Recommended by the IIR

Note de compréhension de certains phénomènes applicables à la maîtrise de la chaine du froid des vaccins.

Note on the understanding of certain phenomena applicable to the control of the vaccine cold chain.

• Author(s) : AFF
• Publication date: 2021/02
• Languages : French
• Keywords : Vaccine, Cold chain, Quality, Review, Generality
• Formats : PDF

Recommended by the IIR / IIR document

COVID 19 vaccine distribution solution to the last mile challenge: Experimental and simulation studies of ultra-low temperature refrigeration system.

• Author(s) : SUN J., ZHANG M., GEHL A., FRICKE B., NAWAZ K., GLUESENKAMP K., SHEN B., MUNK J., HAGERMAN J., LAPSA M.
• Publication date: 2022/01
• Languages : English
• Keywords : Vaccine, COVID-19, Refrigerated container, Low temperature, Storage life, Expérimentation, Road transport
• Source: International Journal of Refrigeration - Revue Internationale du Froid - vol. 133
• Formats : PDF

IIR document

Freezers family for vaccines and cell materials storage within the temperature range of -90 °C to -150 °C. Research and development features.

• Author(s) : MOSTYTSKYI A., BAKLAN O., LITVINENKO M., PEKARYK O., KOKUL S.
• Publication date: 2021/10/05
• Languages : English
• Keywords : Cryotemperature, Vaccine, Cell, Freezer, CO2, Compressor, COP, Energy efficiency, Expérimentation
• Source: Cryogenics 2021 online. Proceedings of the 16^th IIR International Conference, October 5-7, 2021.
• Formats : PDF

Vaccine storage and cold chain monitoring in the North West region of Cameroon: a cross sectional study.

• Author(s) : YAKUM N. M., ATEUDJIEU J., WALTER E. A., et al.
• Publication date: 2015
• Languages : English
• Keywords : Vaccine, Cold chain, Cameroon, Monitoring
• Source: BMC Research Notes
• Formats : PDF

Ensilication improves the thermal stability of the tuberculosis antigen Ag85b and an Sbi-Ag85b vaccine conjugate.

• Author(s) : WAHID A. A., SARTBAEVA A., VAN DEN ELSEN J. M. H.
• Publication date: 2019/08/08
• Languages : English
• Keywords : Vaccine, Silica, Stability, Developing country, Expérimentation
• Source: Nature Scientific Reports - vol. 9

IIR document

Conception and experimental study of a solar vaccine refrigerator powered by a hybrid system.

• Author(s) : OUALI M., ABBAD B., BOUABDALLAH A.
• Publication date: 2014/06/23
• Languages : English
• Keywords : Vaccine, Energy consumption, Cooling, Compression system, Expérimentation, Solar energy, Hot climate
• Source: 3^rd IIR International Conference on Sustainability and the Cold Chain. Proceedings: London, UK, June 23-25, 2014
• Formats : PDF

IIR document

First field test results of a solar thermal off-grid refrigerator for vaccines.

• Author(s) : KÜHN R., MÄHNE K., DÜWEL K., et al.
• Publication date: 2019/08/24
• Languages : English
• Keywords : Vaccine, Solar collector, Medical application, Temperature, Refrigerator, R717, Adsorption, Prototype, Performance, Testing
• Source: Proceedings of the 25^th IIR International Congress of Refrigeration: Montréal , Canada, August 24-30, 2019.
• Formats : PDF

IIR document

Dry ice standalone solutions to transport Covid-19 vaccines.

• Author(s) : KACIMI A., LABRANQUE G., CAVALIER G.
• Publication date: 2022/04/11
• Languages : English
• Keywords : Vaccine, COVID-19, Dry ice, Cold chain, Insulation, Performance, Testing, Box, Insulating panel, Air transport, Expérimentation
• Source: 7^th IIR International Conference on Sustainability and the Cold Chain (Online). Proceedings: April 11-13 2022
• Formats : PDF

IIR document

Extending the autonomy time of an icelined solar powered vaccine cooler.

• Author(s) : JENSEN J. K., BUSK C., CORDING C., et al.
• Publication date: 2019/08/24
• Languages : English
• Keywords : Vaccine, Ice, Heat transfer coefficient, Cabinet, Biot, Cooling, Modelling, Solar energy, Thermal energy storage
• Source: Proceedings of the 25^th IIR International Congress of Refrigeration: Montréal , Canada, August 24-30, 2019.
• Formats : PDF

Management of COVID-19 vaccines cold chain logistics: a scoping review.

• Author(s) : FAHRNI M. L ., ISMAIL I. A., REFI D. M., ALMEMAN A., YAAKOB N. C., SAMAN K. M. , MANSOR N. F. , NOORDIN N., BABAR Z. U.
• Publication date: 2022
• Languages : English
• Keywords : Vaccine, Cold chain, COVID-19, Review, Internet of Things, Refrigerated transport, Developing country
• Source: Journal of Pharmaceutical Policy and Practice - vol. 15
• Formats : PDF

Indian cold chain for vaccines

India has one of the largest Universal Immunization Programs (UIPs) in the world in terms of quantities of vaccines used, number of beneficiaries (27 million infants and 30 million pregnant women), geographical spread and manpower involved and...

• Publication date : 2012/07/10

India: temperature abuse warning via SMS for vaccines

The device is meant to SMS authorities on faulty vaccine carriers.

• Publication date : 2012/11/16

Briefs: Solar vaccine fridges for hot countries

Storing vaccines can be difficult in areas with insufficient electric grids, and renewable energies are increasingly being used as a solution. Two companies specializing in renewable energy technologies are to supply vaccine fridges to Nigeria and...

• Publication date : 2008/05/13

Solar cooling: Low-cost solar vaccine refrigerator

About 2 million people around the world die each year of diseases preventable by widely used vaccines. In Africa and parts of Asia, over half of all vaccines that require refrigeration spoil before they can be administered. Millions of lives and...

• Publication date : 2011/02/04

Vaccines: a step towards thermostability

Ensilication of the protein molecules of a vaccine against tuberculosis prevents its deterioration by heat.

• Publication date : 2019/10/30
• Subjects: Developing country

Low temperature transport and storage solutions for COVID-19 vaccines

Presentation of two options suitable for mRNA vaccines: one using a traditional refrigerated container adapted to storage at -35°C extending the shelf life of dry ice by 2.5 times, the other based on PCM...

• Publication date : 2022/01/28

The challenge of the COVID-19 vaccines cold chain in Africa

A large proportion of African countries do not have the necessary infrastructure for the storage of vaccines at low temperatures. Solar cooling can be a solution in rural areas. 

• Publication date : 2021/02/23
• Subjects: Developing country

A refrigerated bag to preserve vaccines in hot climates

An autonomous refrigerated bag is currently developed in Burkina Faso. It could preserve vaccines between 2 ans 8 °C.

• Publication date : 2017/09/15
• Subjects: Developing country

Vaccine storage management in India

A program providing real-time information on stock and storage temperature of vaccines across cold chain points helps to avoid stock-out situations.

• Publication date : 2018/05/17

Ultra-low temperature systems ready for COVID-19 vaccine storage

Mirai Intex, corporate member of the IIR, is positioning its ultra-low-temperature (ULT) systems to serve as the refrigeration technology for the storage of COVID-19 vaccines and the freeze-drying of the...

• Publication date : 2020/11/26

SOFRIGAM at the heart of the cold chain for the COVID-19 vaccine

The French company SOFRIGAM, a member of the IIR for more than 10 years, has received a qualification for its packaging that enables vaccines against COVID-19  to be stored at very low...

• Publication date : 2021/01/27

Portable “mini-fridge” to maintain vaccine temperature.

A new system, called Isobar, is specifically designed to maintain stable temperature control between 2 and 8°C, up to 30 days.

• Publication date : 2017/02/13
• Subjects: Developing country

The challenges of vaccinating against rabies in hot countries

A large campaign of dog vaccination is currently being conducted in hot countries, raising the issue of the conservation temperature of vaccines.

• Publication date : 2018/03/07
• Subjects: Developing country

Experimental vaccination for Ebola in the Democratic Republic of the Congo

To halt the spread of an outbreak of the Ebola virus in Democratic Republic of the Congo, health workers began an immunisation campaign using vaccines which have to be stored at extremely low temperatures.

• Publication date : 2018/06/22

Refrigeration, a key player to eradicate malaria

Refrigeration techniques have been used to develop and preserve the very first malaria vaccine, which has been administered to almost 2 million children since 2019.

• Publication date : 2024/04/25
• Subjects: Developing country

Webinar on the vaccines against COVID-19

The AFF (French association of refrigeration)  organised a webinar on February 17 on the cold chain related to COVID-19 vaccines.

• Publication date : 2021/02/23

IIR/UNEP Cold Chain Technology Brief on Vaccines

The IIR and the UN Environment programme have jointly developed the cold chain technology brief on vaccines dedicated to government National Ozone Officers, policy makers, and refrigeration stakeholders. The...

• Publication date : 2021/09/08

The IIR and UNEP release a Cold Chain Technology Brief on Vaccines

The International Institute of Refrigeration (IIR) and the UN Environment Programme partnered in the development of a cold chain technology brief on vaccines dedicated to government National Ozone Officers,...

• Publication date : 2021/09/24
• Subjects: Technology

Professionals, participate in a questionnaire on the cold chain of COVID-19 vaccines (in French)

The AFF (French Association of Refrigeration) has just posted a short online questionnaire for vaccines cold chain professionals in order to enrich the work of its...

• Publication date : 2021/10/25
• Subjects: Regulation, Technology

The Cold Chain: A logistical challenge at the heart of the distribution of the COVID-19 vaccine 

Gérald Cavalier - President of the Science and Technology Council of the International Institute of Refrigeration, President of the French Association of Refrigeration, President of the Cemafroid...

• Publication date : 2020/11/23
• Subjects: General information, Technology

Latest news from B-Medical Systems, Epta and GEA, three IIR corporate members

B Medical Systems, a global leader in the vaccine cold chain, is expanding its production capacity due to the COVID-19 pandemic, Epta monitors R290 fridges in cashier-free store in Dubai and GEA provides a...

• Publication date : 2021/11/29

News from IIR members: Sofrigam

Sofrigam has launched a new range of refrigerated pouches designed to secure the transport of vaccines throughout the cold chain right up to the last link, i.e. pharmacists, medical practitioners, nurses and patients. Sizes range from single doses...

• Publication date : 2010/02/18

News from IIR members: Sofrigam

Sofrigam has launched a new range of refrigerated pouches designed to secure the transport of vaccines throughout the cold chain right up to the last link, i.e. pharmacists, medical practitioners, nurses and patients. Sizes range from single doses...

• Publication date : 2010/03/07

News from IIR members: Sofrigam

The number of drugs (e.g. targeted therapies, new vaccines, anti-diabetic drugs and blood derivatives) transported and kept at a controlled temperature is growing rapidly and these products are increasingly sensitive to temperature variations. In...

• Publication date : 2008/08/12

COP 28: the annual conference on climate change puts refrigeration in the spotlight!

Refrigeration will be one of the priorities at the next United Nations Conference of the Parties on climate change. It will be held in Dubai from 30 November to 12 December 2023. 

• Publication date : 2023/11/24

Healthcare ColDays 2022: innovations in refrigeration and health

The French Association of Refrigeration (Association Française du Froid) is organising a day dedicated to the latest technical and scientific developments in the field of refrigeration and health on 26 April...

• Publication date : 2022/02/04

Celebrating Refrigeration Ceremony 2021

Organised under the initiative of the French Association of Refrigeration (AFF), the third French New Year ceremony to celebrate refrigeration, Les Vœux du Froid, took place on January 21.

• Publication date : 2021/01/27

Best Wishes 2021!

The IIR wishes you all the best for the new year!

• Publication date : 2021/01/07

Statement given by Didier Coulomb, Director General of the IIR, during MOP 31

Statement Given by the Director General of the International Institute of Refrigeration (IIR) during the 31st Meeting of the Parties to the Montreal Protocol (MOP-31) in Rome (November 4-8,...

• Publication date : 2020/04/03
• Subjects: Developing country, Regulation, Environment

Refrigeration and the IIR in the spotlight at COP 28

The Conference of the Parties on Climate Change took place in Dubai (United Arab Emirates) from 30 November to 13 December 2023. For the first time, refrigeration was given special attention. The IIR shared a...

• Publication date : 2023/12/18
• Subjects: Environment

Cryogenics in the pharmaceutical industry: drug design and bioavailability improvement

Research activities in the pharmaceutical sector focus primarily on developing novel drug formulations which can elicit the desired response upon being administered to the patient...

• Last update : 2023/03/10
• Langues : English, French
• Themes : Freeze-drying in biology and medicine, Cryobiology, cryomedicine: general information