Discover the 30th Informatory Note on Heat-Sensitive Health Products

In this Informatory Note, the IIR has defined the issues and challenges that need to be addressed in order to ensure that reliable cold chains, along the distribution chain of products essential to public health, are put in place.

The 30th Informatory Note on Refrigeration Technologies



Heat-Sensitive Health Products


A significant number of health products (vaccines, insulin, labile blood products, biotechnology products, tissue, organs etc.) are heat-sensitive and a change in their storage temperature can render them unusable, inefficient, even dangerous.


Among the top 10 medicines sold across the world, only one does not have any specific temperature requirements.

Confronting the issues raised with regards to the temperature control of these health products throughout the distribution chain is essential, with health and economic factors being the priority.


In this Informatory Note, the IIR has defined the issues and challenges that need to be addressed in order to ensure that reliable cold chains, along the distribution chain of products essential to public health, are put in place.



This Informatory Note was prepared by Gérald Cavalier (Member of the IIR Executive Committee and President of Section D Storage and Transport) and Marie Boned.

It was reviewed by several experts from the IIR commissions.




Only IIR members can currently download this note.

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Consult the 30th Informatory Note on Heat-Sensitive Health Products

See all of our previous Informatory Notes




About IIR Informatory Notes

The IIR publishes Informatory Notes designed to meet the needs of decision-makers worldwide, on a regular basis. These notes summarize knowledge in key refrigeration-technology and refrigeration-application domains. Each note puts forward future priority developmental axes and provides IIR recommendations in this context.