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An experimental study of the mechanical response of frozen biological tissues at cryogenic temperatures.

Author(s) : RABIN Y., STEIF P. S., TAYLOR M. J., JULIAN T. B., WOLMARK N.

Type of article: Article

Summary

The main concept in this study is that the stresses associated with the constrained contraction of the frozen tissue, i.e. due to temperature variations within the frozen tissue, can be simulated by an external mechanical load which is applied to the frozen tissue while the tissue is maintained at a uniform temperature. A new apparatus for measuring compressive stresses and strains of frozen biological tissues in cryogenic temperature range is presented. An unusual response of frozen biological tissues to compressive stress was observed: after the initial, roughly linear elastic portion there was a series of sudden stress drops at constant strain, each followed by a linear increase of stress with strain to the next drop. This phenomenon, which is attributed to the accumulation of microcracks, broadly resembles plastic deformation.

Details

  • Original title: An experimental study of the mechanical response of frozen biological tissues at cryogenic temperatures.
  • Record ID : 1997-1151
  • Languages: English
  • Source: Cryobiology - vol. 33 - n. 4
  • Publication date: 1996/08

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