Share

IIR document

Cryosurgery: advances in the application of low temperatures to medicine.

Author(s) : RUBINSKY B., ONIK G.

Type of article: Article, IJR article

Summary

Among the many applications of low temperature in medicine, the most significant recent advances have occurred in cryosurgery, Cryosurgery, the in situ freezing of undesirable tissue, may become an important technique in the treatment of large solid tumours which are drug resistant. Despite excellent results with some types of cancer, e.g. skin, cryosurgery is not widely accepted by surgeons because of difficulties in controlling the procedure. This is a consequence of both the lack of information on the mechanism of damage during cryosurgery and the difficulty in observing in real time the transient, irregular shape of the frozen region during surgery. Recent advances, which have, in part, overcome these problems will be discussed herein. A new experimental technique using directional solidification and low temperature scanning electron microscopy for the study of the process of freezing during cryosurgery will be presented, New mathematical models for the process of freezing during cryosurgery, derived from experimental data, will also be described. The use of new real-time imaging techniques, such as intraoperative ultrasound, for monitoring the process of freezing will be introduced. Finally, the successful application of these new techniques in the treatment of non-resectable metastatic turnouts in the liver will be described.

Available documents

Format PDF

Pages: 190-199

Available

  • Public price

    20 €

  • Member price*

    Free

* Best rate depending on membership category (see the detailed benefits of individual and corporate memberships).

Details

  • Original title: Cryosurgery: advances in the application of low temperatures to medicine.
  • Record ID : 30001883
  • Languages: English
  • Source: International Journal of Refrigeration - Revue Internationale du Froid - vol. 14 - n. 4
  • Publication date: 1991/07

Links


See other articles in this issue (6)
See the source

Indexing