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EFFECTS OF CRYOSURGERY IN EXPERIMENTAL CARCINOMA ON LECTIN BINDING AND KERATIN DISTRIBUTION.

Author(s) : NINOMIYA T., HIGASHIYAMA H., MORI M.

Type of article: Article

Summary

HISTOCHEMICAL ALTERATIONS OF LECTIN BINDING AND KERATIN DISTRIBUTION IN EXPERIMENTAL CARCINOMAS OF THE HAMSTER CHEEK POUCH WERE OBTAINED FOLLOWING CRYOTREATMENT. CRYOTREATED CARNINOMA CELLS SHOWED A CHARACTERISTIC REDUCTION IN LECTIN BINDING AND KERATIN STAINING SHORTLY FOLLOWING CRYOSURGERY. TUMOUR TISSUE, ON THE 2ND AND 3RD DAYS AFTER CRYOTREATMENT, DISPLAYED DESTRUCTION AND NECROSIS WITH ALMOST A COMPLETE LOSS OF LECTIN BINDING AND KERATIN STAINING. THE REMAINING NEOPLASTIC CELLS LOCATED IN THE DEEPER LAYERSHOWED POSITIVE REACTION FOR BOTH LECTIN BINDING AND KERATIN, WHICH IS INDICATIVE OF TUMOUR RUCURRENCE. HISTOCHEMICAL STAINING OF LECTIN BINDING AND KERATIN PROTEINS WERE USEFUL MARKERS IN CRYOTREATED TUMOUR CELLS.

Details

  • Original title: EFFECTS OF CRYOSURGERY IN EXPERIMENTAL CARCINOMA ON LECTIN BINDING AND KERATIN DISTRIBUTION.
  • Record ID : 1986-2114
  • Languages: English
  • Source: Cryobiology - vol. 22 - n. 6
  • Publication date: 1985

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