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Evaluation of cryosurgery for synchronized liver metastasis from colorectal cancer.

[In Japanese. / En japonais.]

Author(s) : WATANABE M., NAKAZAKI H., TAKADA M., et al.

Type of article: Article

Summary

The authors examined whether cryosurgery of the liver contributed to the prognosis of patients who had synchronized liver metastasis from colorectal cancer. Twelve patients, whose prognosis after the cryosurgery was clear, were eligible. All patients received, not only resection of the colorectal primary lesion, but also cryosurgery for liver metastasis under the same laparotomy. These patients were treated in this manner from 1981 to 1987. Ten of the 12 patients died from recurrent cancer. Two patients died from other causes, one was cancer free at 117 months and the other one, who died at 24 months, had localized cancer of the liver with pulmonary metastasis. The range of survival time of 12 cases was from 6 to 117 months with an average of 25.4 months. Although it is suggested that cryosurgery induces an immunological response, it was not definitively demonstrated that there was a specific association between the patients' improved prognosis and an immune response. Patients with small versus large hepatic tumours had a better prognosis for the successful application of cryosurgery. The survival time of 17 months and 22 months in two patients in which only their metastasis were treated was very good.

Details

  • Original title: [In Japanese. / En japonais.]
  • Record ID : 2004-2535
  • Languages: Japanese
  • Source: Low Temperature Medicine - vol. 28 - n. 4
  • Publication date: 2002/12
  • Document available for consultation in the library of the IIR headquarters only.

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