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FUNDAMENTALS OF FREEZE-DRYING PHARMACEUTICALS.

Author(s) : DELUCA P. P.

Summary

INITIAL FREEZING IS OF CRITICAL IMPORTANCE SINCE IT WILL INFLUENCE SUBLIMATION. SUITABLE COOLING CYCLES PROVIDE A CORRECT STRUCTURE. IF THE FROZEN SYSTEM EXHIBITS A METASTABLE EQUILIBRIUM OF GLASSY STRUCTURES, APPROPRIATE THERMAL TREATMENTS WILL BE NECESSARY FOR PRODUCING THE CRYSTALLIZATION OF THE METASTABLE MATERIAL AND AN ADEQUATE CRYSTAL SIZE WILL BE NECESSARY FOR EFFICIENT SUBLIMATION.

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Pages: 1985-1

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Details

  • Original title: FUNDAMENTALS OF FREEZE-DRYING PHARMACEUTICALS.
  • Record ID : 1987-0778
  • Languages: English
  • Source: Fundamentals and Applications of Freeze-Drying to Biological Materials, Drugs and Foodstuffs.
  • Publication date: 1985/05/20
  • Document available for consultation in the library of the IIR headquarters only.

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