INVESTIGATION OF PROTECTIVE AGENTS AGAINST OXIDATIVE STRESS DURING HYPOTHERMIC STORAGE OF PIG KIDNEYS.

Author(s) : FULLER B. J.

Type of article: Article

Summary

PORCINE KIDNEYS WERE STORED IN ICE FOR 24 HOURS AFTER VASCULAR FLUSH USING PHOSPHATE-BUFFERED SALINE. THIS STRESS WAS ASSOCIATED WITH EVIDENCE OF LIPID PEROXIDATION WHEN THE KIDNEY TISSUES WERE SUBJECTED TO IN VITRO INCUBATION, WHICH MAY HAVE RESULTED FROM INTERACTION OF TISSUE POLYUNSATURATED FATTY ACIDS WITH OXYGEN-DERIVED FREE RADICALS. A SIMILAR PHENOMENON HAS BEEN NOTED IN RABBIT KIDNEYS AND THUS MAY GENERALLY REFLECT HYPOTHERMIC RENAL DAMAGE IN MAMMALIAN SPECIES.

Details

  • Original title: INVESTIGATION OF PROTECTIVE AGENTS AGAINST OXIDATIVE STRESS DURING HYPOTHERMIC STORAGE OF PIG KIDNEYS.
  • Record ID : 1986-2109
  • Languages: English
  • Source: Cryo-Letters - vol. 7 - n. 2
  • Publication date: 1986
  • Document available for consultation in the library of the IIR headquarters only.

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