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PROGRESS IN CRYOSURGERY.

Author(s) : ABLIN R. J.

Summary

CRYOSURGERY HAS BEEN USED EFFICIENTLY FOR THE TREATMENT OF BENIGN AND MALIGNANT NEOPLASMS. THE STUDY OF THE EFFECTS OF THE IN SITU FREEZING OF SOME NORMAL OR PATHOLOGICAL TISSUES SHOWED AN IMMUNOLOGIC RESPONSE TO THE ANTIGENS OF THE FROZEN TISSUE, THEREFORE CRYOIMMUNISATION CONTRIBUTING TO CRYODESTRUCTION. IF CRYOSURGERY HAS TO BE USED NOT ONLY FOR THE CRYODESTRUCTION OF THE TUMOUR BUT ALSO AS A POSSIBLE MEAN FOR PRODUCING AN IMMUNOLOGIC RESPONSE TO THE TUMOUR (PRIMARY OR SECONDARY, IE TO METASTASES), SEVERAL FACTORS SHOULD BE CAREFULLY CONSIDERED: 1. THE IMMUNOGENICITY OF THE TISSUE TREATED BY CRYOSURGERY, 2. THE IMMUNOCOMPETENCE OF THE HOST. A SUPPLEMENTARY USE OF IMMUNOMODULATORS IS SUGGESTED IN ORDER TO INCREASE THE FAVOURABLE EFFECTS, OR SUPPRESSING THOSE NOXIOUS, OF CRYOIMMUNOTHERAPY AND TO OBTAIN A REALLY EFFICIENT APPLICATION.

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Pages: 155-162

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Details

  • Original title: PROGRESS IN CRYOSURGERY.
  • Record ID : 1986-0892
  • Languages: English
  • Source: [Refrigeration serving humanity]. Proceedings of the XVIth international Congress of Refrigeration.
  • Publication date: 1983/08/07
  • Document available for consultation in the library of the IIR headquarters only.

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