THE MECHANISM OF STRUCTURAL AND OSMOTIC ADAPTATION OF ERYTHROCYTES TO CRYOPRESERVATION.
Author(s) : BABIYCHUK L. A., ZEMLYANSKIKH N. G.
Summary
THE AUTHORS FOUND IN THEIR EXPERIMENTS THAT STEPWISE COLD TREATMENT OF ERYTHROCYTES WITH AN IMPERMEABLE CRYOPROTECTANT POLYETHYLENE OXIDE OF MOLECULAR WEIGHT 1500 (PEO-1500) FAVOURS THE DEVELOPMENT OF INCREASED CELL RESISTANCE TO SUBSEQUENT FREEZE-THAWING. THIS CAN BE SEEN IN A SHARP DECREASE OF HEMOLYSIS AND OSMOTIC FRAGILITY OF ERYTHROCYTES AFTER TRANSFER TO MEDIA OF PHYSIOLOGICAL TONICITY, WHEN COMPARED TO CELLS TREATED AT ROOM TEMPERATURE.
Details
- Original title: THE MECHANISM OF STRUCTURAL AND OSMOTIC ADAPTATION OF ERYTHROCYTES TO CRYOPRESERVATION.
- Record ID : 1990-2145
- Languages: English
- Publication date: 1989/07/06
- Source: Source: Proc. IVth int. Sch. Cryobiol. Freeze-drying, Borovets
L31-L33; 4 fig.; 1 tabl. - Document available for consultation in the library of the IIR headquarters only.
Indexing
-
CRYOPRESERVATION OF ERYTHROCYTES. THE ROLE OF C...
- Author(s) : BELOUS A. M.
- Date : 1990
- Languages : English
- Source: Cryo-Letters - vol. 11 - n. 6
View record
-
A STUDY OF THE SEPARATE EFFECTS OF INFLUENCE FA...
- Author(s) : GAO D. Y.
- Date : 1989
- Languages : English
- Source: Cryobiology - vol. 26 - n. 4,1989.08
View record
-
THE EFFECT OF MECHANICAL FACTOR ON THE CELL DAM...
- Author(s) : VOROTILIN A. M.
- Date : 1988
- Languages : Russian
- Source: Kriobiologija - n. 3
View record
-
THE EFFECT OF COOLING RATE AND WARMING RATE ON ...
- Author(s) : PEGG D. E.
- Date : 1984
- Languages : English
- Source: Cryobiology - vol. 21 - n. 5
View record
-
CRYOPROTECTION OF RED BLOOD CELLS BY 1,3-BUTANE...
- Author(s) : MEHL P., BOUTRON P.
- Date : 1988
- Languages : English
- Source: Cryobiology - vol. 25 - n. 1
View record