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The operation and efficacy of cryosurgical, nitrous oxide-driven cryoprobe.

Author(s) : HOMASSON J. P., THIERY J. P., ANGEBAULT M., OVTRACHT L., MAIWAND O.

Type of article: Article

Summary

The cryoprobe was a 3-mm-diameter type for operation via fiber optic bronchoscopes in respiratory medicine. The freezing process, namely the "ice-ball" formation around the cryoprobe tip, was monitored with an impedancemeter. Tests showed that cryotoxicity correlated with freezing rate within the ice ball, that cell mortality was total next to the cryoprobe tip, while it was absent within the ice-ball periphery. Results show that cryotoxicity to cells may be improved by increasing the freezing rate, and higher efficacy might be achieved by several overlapping short freezing spots in tumoral tissue, instead of one single prolonged freeze.

Details

  • Original title: The operation and efficacy of cryosurgical, nitrous oxide-driven cryoprobe.
  • Record ID : 1995-0581
  • Languages: English
  • Source: Cryobiology - vol. 31 - n. 3
  • Publication date: 1994/06

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