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THERAPEUTIC EFFECT OF CRYOSURGERY OF MURINE OSTEOSARCOMA: INFLUENCE ON DISEASE OUTCOME AND IMMUNE FUNCTION.

Author(s) : MULLER L. C.

Type of article: Article

Summary

EXPERIMENTS COMPARING CONVENTIONAL OPERATIVE TREATMENT AND CRYOSURGERY OF A MURINE OSTEOSARCOMA SHOWED THAT LOCAL TUMOUR DESTRUCTION BY FREEZING IN SITU WAS SIMILAR OR SUPERIOR TO AMPUTATION CONCERNING SURVIVAL AND FORMATION OF METASTASIS, DEPENDING ON TUMOUR STAGE. LIMITED LOCAL RESECTION WAS LESS EFFECTIVE. IMMUNE FUNCTIONS AFFECTED BYCRYOSURGICAL TUMOUR DESTRUCTION INCLUDED DEPRESSION OF NATURAL KILLER CELL ACTIVITY AND DECREASE OF TUMOUR-SPECIFIC AUTOLOGOUS ANTIBODIES IN THE SERUM.

Details

  • Original title: THERAPEUTIC EFFECT OF CRYOSURGERY OF MURINE OSTEOSARCOMA: INFLUENCE ON DISEASE OUTCOME AND IMMUNE FUNCTION.
  • Record ID : 1985-2691
  • Languages: English
  • Source: Cryobiology - vol. 22 - n. 1
  • Publication date: 1985

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