ShareTumour fixation of bleomycin labelled with 57 cobalt before and after cryotherapy of bronchial carcinoma.
Author(s) : HOMASSON J. P., PECKING A., RODEN S., ANGEBAULT M., BONNIOT J. P.
Type of article: Article
Summary
A mean increase of 30% of radiolabeled bleomycin was found in the tumour area after cryotherapy, and pharmacokinetic data were significantly different after cryotherapy. The vascular component of cryodestruction offers an explanation for these results, with trapping of the anticancer drug in the tumour and immediately surrounding area due to vascular stasis. It seems that chemotherapy may be more effective after cryotherapy, and a multicenter study is in progress to evaluate the association of cryo-chemotherapy in France.
Details
- Original title: Tumour fixation of bleomycin labelled with 57 cobalt before and after cryotherapy of bronchial carcinoma.
- Record ID : 1994-1901
- Languages: English
- Source: Cryobiology - vol. 29 - n. 5
- Publication date: 1992/10
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