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IIR document

Cryoprotective effect of carboxylated poly-L-lysine on the nematode Caenorhabditis elegans.

• Author(s) : HAYASHI M., MURASE N., MATSUMURA K.
• Publication date: 2015/08/16
• Languages : English
• Source: Proceedings of the 24th IIR International Congress of Refrigeration: Yokohama, Japan, August 16-22, 2015.
• Formats : PDF

Analysis of supercooling activity of tannin-related polyphenols.

• Author(s) : KUWABARA C., WANG D., ENDOH K., et al.
• Publication date: 2013/08
• Languages : English
• Source: Cryobiology - vol. 67 - n. 1

Recommended by the IIR / IIR document

Vaccine cold-chain challenges for fast-track mass COVID-19 vaccination in Bangladesh.

• Author(s) : MUNSHI F., DEBNATH S., SENAN A., PETERS T., GREENING P., WANG X.
• Publication date: 2022/04/11
• Languages : English
• Keywords : Vaccine, COVID-19, Bangladesh, Cold chain, Survey
• Source: 7^th IIR International Conference on Sustainability and the Cold Chain Online. Proceedings: April 11-13 2022
• Formats : PDF

Cryopreservation in a Standard Freezer: −28 °C as Alternative Storage Temperature for Amniotic Membrane Transplantation.

• Author(s) : WITT J., GRUMM L., SALLA S., GEERLING G., MENZEL-SEVERING J.
• Publication date: 2022/02
• Languages : English
• Source: Journal of Clinical Medicine - 11 - 4
• Formats : PDF

Recommended by the IIR

Les règles et bonnes pratiques du travail au froid à -20 °C.

The rules and good practices for working at temperatures as low as -20°C.

• Author(s) : AFF
• Publication date: 2021/02
• Languages : French
• Keywords : Vaccine, Safety, Low temperature, Recommendation, Generality
• Formats : PDF

Explorative Supercooling Technology for Prevention of Freeze Damages in Vaccines.

• Author(s) : JUN S., KO Y., LEE S. H.
• Publication date: 2022/03
• Languages : English
• Keywords : Supercooling, Design, Vaccine, Temperature, Temperature variation, Magnetic field, Cold chain, Testing
• Source: Applied Sciences - 12 - 6
• Formats : PDF

Recommended by the IIR

Bonnes pratiques d’usage et signification des marquages des emballages isothermes utilisant la glace carbonique comme source de froid.

Good usage practices and meaning of markings on isothermal packaging using dry ice as a source of cold.

• Author(s) : AFF
• Publication date: 2021/02
• Languages : French
• Keywords : Packaging, Vaccine, Low temperature, Dry ice, Generality
• Formats : PDF

High cryo-resistance of SARS-CoV-2 virus: Increased risk of re-contamination at transplantation of cryopreserved ovarian tissue after COVID-19 pandemic.

• Author(s) : ISACHENKO V., ISACHENKO E., MALLMANN P., RAHIMI G.
• Publication date: 2021/12
• Languages : English
• Keywords : COVID-19, Cancer, Virus, Cryopreservation, Cryostability, Contamination, Organ, Freeze-drying, Review
• Source: Cryobiology - vol. 103
• Formats : PDF

IIR document

Study on proline as cryoprotectant in cryopreservation.

• Author(s) : SUN Z., LI Y., RAO W.
• Publication date: 2019/08/24
• Languages : English
• Source: Proceedings of the 25^th IIR International Congress of Refrigeration: Montréal , Canada, August 24-30, 2019.
• Formats : PDF

IIR document

Cryopreservation: methods, equipment and critical concerns.

• Author(s) : NANNOU T. K., TREMBLEY J., HERRMANN J., et al.
• Publication date: 2016/06/22
• Languages : English
• Source: 1^st IIR International Conference of Cryogenics and Refrigeration Technology (ICCRT 2016). Proceedings: Bucharest, Romania, June 22-25, 2016.
• Formats : PDF

Anti-ice nucleating activity of polyphenol compounds against silver iodide.

• Author(s) : KOYAMA T., INADA T., KUWABARA C., et al.
• Publication date: 2014/10
• Languages : English
• Source: Cryobiology - vol. 69 - n. 2

Vacciner les enfants au-delà de la "chaine de froid" : pour des vaccins moins sensibles à la chaleur.

Vaccinating children beyond the cold chain: towards less heat-sensitive vaccines.

• Publication date: 2014/04
• Languages : French
• Keywords : Vaccine, Heat, Controlled atmosphere, Cold chain, Transport, Quality, Developing country, Distribution

IIR document

Criteria for capability of measuring instruments used in the cold chain of health products.

• Author(s) : DEVIN E.
• Publication date: 2013/04/02
• Languages : English
• Source: 2^nd IIR International Conference on Sustainability and the Cold Chain. Proceedings: Paris, France, April 2-4, 2013.
• Formats : PDF

IIR document

Heat-Sensitive Health Products, 30th Informatory Note on refrigeration technologies.

• Author(s) : IIF-IIR, CAVALIER G., BONED M.
• Publication date: 2016/01
• Languages : English, French
• Keywords : Vaccine, Economy, Cold chain, Medical application, Measurement, Temperature, Monitoring, Storage, Health product, Pharmaceutical industry
• Formats : PDF

Recommended by the IIR

Note de compréhension de certains phénomènes applicables à la maîtrise de la chaine du froid des vaccins.

Note on the understanding of certain phenomena applicable to the control of the vaccine cold chain.

• Author(s) : AFF
• Publication date: 2021/02
• Languages : French
• Keywords : Vaccine, Cold chain, Quality, Review, Generality
• Formats : PDF

Siberian nematode worms kept in permafrost for 42,000 years come back to life

A team of Russian researchers revived two nematodes buried in Siberian permafrost for 32,000 and 42,000 years.

• Publication date : 2018/09/20

Refrigeration technologies help preserve biodiversity

The role of refrigeration in biodiversity protection is illustrated by two examples: the cryopreservation of coral larvae and the use of refrigeration to fight bee colony collapse.

• Publication date : 2019/05/29
• Subjects: Environment, General information

Recovery and reproduction of tardigrades frozen for over 30 years

Scientists managed to resuscitate tardigrades and have them reproduce although they had been frozen since 1983!

• Publication date : 2016/08/17

Vaccines: a step towards thermostability

Ensilication of the protein molecules of a vaccine against tuberculosis prevents its deterioration by heat.

• Publication date : 2019/10/30
• Subjects: Developing country

Ultra-low temperature systems ready for COVID-19 vaccine storage

Mirai Intex, corporate member of the IIR, is positioning its ultra-low-temperature (ULT) systems to serve as the refrigeration technology for the storage of COVID-19 vaccines and the freeze-drying of the...

• Publication date : 2020/11/26

Low temperature transport and storage solutions for COVID-19 vaccines

Presentation of two options suitable for mRNA vaccines: one using a traditional refrigerated container adapted to storage at -35°C extending the shelf life of dry ice by 2.5 times, the other based on PCM...

• Publication date : 2022/01/28

Simplifying the preservation at very low temperature of tissues used in ophthalmology

Researchers have compared the effects of −28 °C (standard freezer) and −80 °C preservation on human amniotic membrane, which is commonly used in ophthalmic...

• Publication date : 2022/05/30
• Subjects: Technology

The challenge of cold chain breaches in a medical setting

In an article published in the Journal of Clinical Pharmacy and Therapeutics, researchers from the University of Canberra highlight the need for further research into the preservation of medicines and the maintenance of the cold chain.

• Publication date : 2018/08/08

Experimental vaccination for Ebola in the Democratic Republic of the Congo

To halt the spread of an outbreak of the Ebola virus in Democratic Republic of the Congo, health workers began an immunisation campaign using vaccines which have to be stored at extremely low temperatures.

• Publication date : 2018/06/22

Vaccine storage management in India

A program providing real-time information on stock and storage temperature of vaccines across cold chain points helps to avoid stock-out situations.

• Publication date : 2018/05/17

The challenge of the COVID-19 vaccines cold chain in Africa

A large proportion of African countries do not have the necessary infrastructure for the storage of vaccines at low temperatures. Solar cooling can be a solution in rural areas. 

• Publication date : 2021/02/23
• Subjects: Developing country

Portable “mini-fridge” to maintain vaccine temperature.

A new system, called Isobar, is specifically designed to maintain stable temperature control between 2 and 8°C, up to 30 days.

• Publication date : 2017/02/13
• Subjects: Developing country

SOFRIGAM at the heart of the cold chain for the COVID-19 vaccine

The French company SOFRIGAM, a member of the IIR for more than 10 years, has received a qualification for its packaging that enables vaccines against COVID-19  to be stored at very low...

• Publication date : 2021/01/27

Webinar on the vaccines against COVID-19

The AFF (French association of refrigeration)  organised a webinar on February 17 on the cold chain related to COVID-19 vaccines.

• Publication date : 2021/02/23

IIR/UNEP Cold Chain Technology Brief on Vaccines

The IIR and the UN Environment programme have jointly developed the cold chain technology brief on vaccines dedicated to government National Ozone Officers, policy makers, and refrigeration stakeholders. The...

• Publication date : 2021/09/08

Healthcare ColDays 2022: innovations in refrigeration and health

The French Association of Refrigeration (Association Française du Froid) is organising a day dedicated to the latest technical and scientific developments in the field of refrigeration and health on 26 April...

• Publication date : 2022/02/04

Professionals, participate in a questionnaire on the cold chain of COVID-19 vaccines (in French)

The AFF (French Association of Refrigeration) has just posted a short online questionnaire for vaccines cold chain professionals in order to enrich the work of its...

• Publication date : 2021/10/25
• Subjects: Regulation, Technology