A pilot study of cryochemotherapy for hepatic metastases from colorectal cancer.

Summary

Cryosurgery of hepatic metastases from colorectal carcinoma is a form of local therapy for unresectable disease. After curative resection, failures occur in the liver, and at extrahepatic sites. This pilot study with 4 patients evaluated the toxicity and tolerance to cryotherapy and intraoperative chemotherapy for unresectable hepatic metastases from colorectal cancer. Combining the tumoricidal effects of chemotherapy and cryosurgery is in theory a good concept. However, the toxicity of 5-fluorouracil and leucovirin is enhanced by this approach.

Details

  • Original title: A pilot study of cryochemotherapy for hepatic metastases from colorectal cancer.
  • Record ID : 1998-0608
  • Languages: English
  • Source: Cryobiology - vol. 33 - n. 6
  • Publication date: 1996/12

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