ShareCryochemistry: peptide coupling in frozen organic solution.
Author(s) : VAJDA T.
Type of article: Article
Summary
Examples of peptide coupling in frozen dioxane solution are presented and compared to the results obtained in liquid solution. The protected dipeptides of glycine-alanine-, phenylalanine-alanine, -glycine-phenylalanine and phenylalanine-phenylalanine have been synthetized by using of 4-nitrophenyl active esters for the coupling. The reactions carried out at -18 deg C in frozen conditions produced a significantly higher reaction rate than those of 40 deg C. The role of frozen dioxane in the improved results is discussed.
Details
- Original title: Cryochemistry: peptide coupling in frozen organic solution.
- Record ID : 1997-3039
- Languages: English
- Source: Cryo-Letters - vol. 17 - n. 5
- Publication date: 1996/09
- Document available for consultation in the library of the IIR headquarters only.
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Indexing
- Themes: Cryobiology, cryomedicine: general information
- Keywords: Cryobiology; Solution; Freezing; Amino acid
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Study of the solid-liquid state diagram of the ...
- Author(s) : SHALAEV E. Ju., KANEV A. N.
- Date : 1994/08
- Languages : English
- Source: Cryobiology - vol. 31 - n. 4
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The role of freezing in trypsin activity oscill...
- Author(s) : VAJDA T.
- Date : 1992/08
- Languages : English
- Source: Cryobiology - vol. 29 - n. 4
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Glass-forming tendency and stability of the amo...
- Author(s) : BOUTRON P.
- Date : 1993/02
- Languages : English
- Source: Cryobiology - vol. 30 - n. 1
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HEAT TRANSFER WITH PHASE TRANSITION IN BIOLOGIC...
- Author(s) : RUBINSKY B.
- Date : 1989/05
- Languages : English
- Source: Cryo-Letters - vol. 10 - n. 3
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DEVITRIFICATION IN GLASS-FORMING AQUEOUS SOLUTI...
- Author(s) : MACFARLANE D. R.
- Date : 1986
- Languages : English
- Source: Cryobiology - vol. 23 - n. 3
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