Cryopreservation of rat and human liver slices by rapid freezing.

Author(s) : DAY S. H., NICOLL-GRIFFITH D. A., SILVA J. M.

Type of article: Article

Summary

The cryopreservation of human liver slices is a promising way to enhance the ability to test the metabolism of drug candidates. The study demonstrates the use of a novel technique for the cryopreservation of both rat and human liver slices. The technique was found to work over a wide range of DMSO concentrations (4.5 to 22% was tested) with an optimal concentration between 10 and 15%.

Details

  • Original title: Cryopreservation of rat and human liver slices by rapid freezing.
  • Record ID : 2000-1029
  • Languages: English
  • Source: Cryobiology - vol. 38 - n. 2
  • Publication date: 1999/03

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