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Experimental study on the rehydration of lyophilized human platelets.

Author(s) : FAN J. L., ZHU F. M., ZHANG S. Z., et al.

Summary

Freeze-drying is an ideal alternative for long-term preservation of platelets in blood banks. In this paper, prehydration time, rehydration temperature and rehydration solution were considered for studying the rehydration of freeze-dried human platelets. Three prehydration times, 0, 1.5 and 3.5 h and two rehydration solutions, platelet-poor plasma and phosphate-buffered saline (PBS) were investigated. It is found that prehydration is beneficial and 1. 5 h prehydration time is better than 3.5 h; platelet-poor plasma is better than PBS. These results will be helpful for further study on freeze-drying of mammalian cells.

Details

  • Original title: Experimental study on the rehydration of lyophilized human platelets.
  • Record ID : 2009-0883
  • Languages: English
  • Source: Cryogenics and refrigeration. Proceedings of ICCR'2008.
  • Publication date: 2008/04/05

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