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Freezing injury and free radical generation: increment of intracellular cyclic AMP enhances the osmotic resistance of human polymorphonuclear leukocytes (PMNs) and monocytes.

Author(s) : TAKAHASHI T. A., HOSODA M., SEKIGUCHI S.

Type of article: Article

Summary

Experiments to improve the resistance to osmotic stress of PMNs using various chemical treatments are described and discussed. Those enriched with cyclic adenosine monophosphate (AMP) could tolerate osmotic stresses of 900 (hyper) and 75 mOsm (hypo) whilst retaining phagocytotic and chemotactic properties. G.R.S.

Details

  • Original title: Freezing injury and free radical generation: increment of intracellular cyclic AMP enhances the osmotic resistance of human polymorphonuclear leukocytes (PMNs) and monocytes.
  • Record ID : 1994-1270
  • Languages: English
  • Source: Low Temperature Medicine - vol. 18 - n. 2
  • Publication date: 1992/06
  • Document available for consultation in the library of the IIR headquarters only.

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