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Induction of tolerance to hypothermia by previous heat shock using human fibroblasts in culture.

Author(s) : RUSSOTTI G., BRIEVA T. A., TONER M., YARMUSH M. L.

Type of article: Article

Summary

The level of induced cold tolerance was directly related to the length of the heat shock up to a 5-hour heat shock at which point cold tolerance reached a maximum level. This phenomenon was found to be reversible in that sufficiently long interruptions at 37 deg C between the heat shock and hypothermic exposure resulted in a loss of this cold-tolerant state. Heat shock proteins may be involved in the mechanism.

Details

  • Original title: Induction of tolerance to hypothermia by previous heat shock using human fibroblasts in culture.
  • Record ID : 1997-2480
  • Languages: English
  • Source: Cryobiology - vol. 33 - n. 5
  • Publication date: 1996/10

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