ShareInduction of tolerance to hypothermia by previous heat shock using human fibroblasts in culture.
Author(s) : RUSSOTTI G., BRIEVA T. A., TONER M., YARMUSH M. L.
Type of article: Article
Summary
The level of induced cold tolerance was directly related to the length of the heat shock up to a 5-hour heat shock at which point cold tolerance reached a maximum level. This phenomenon was found to be reversible in that sufficiently long interruptions at 37 deg C between the heat shock and hypothermic exposure resulted in a loss of this cold-tolerant state. Heat shock proteins may be involved in the mechanism.
Details
- Original title: Induction of tolerance to hypothermia by previous heat shock using human fibroblasts in culture.
- Record ID : 1997-2480
- Languages: English
- Source: Cryobiology - vol. 33 - n. 5
- Publication date: 1996/10
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Indexing
- Themes: Cryomedicine and cryosurgery
- Keywords: Heat; Cryobiology; Cold sensitivity; Treatment; Hypothermia; Man
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