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Liver preservation below 0 deg C with UW solution and 2,3 butanediol.

Author(s) : SCOTTE M., ESCHWEGE P., CHERRUAU C., FONTALIRAN F., MOREAU F., HOUSSIN D.

Type of article: Article

Summary

Using this method, preservation of the rat liver below 0 deg C seems feasible. However, despite its low concentration, some toxicity of 2,3-butanediol was suspected. This would counterbalance the benefit resulting from temperature-related decrease of the enzymatic activities involved in cold ischemia damage. The potential advantages of this method need to be confirmed by assessing liver viability using a liver transplantation model.

Details

  • Original title: Liver preservation below 0 deg C with UW solution and 2,3 butanediol.
  • Record ID : 1997-0547
  • Languages: English
  • Source: Cryobiology - vol. 33 - n. 1
  • Publication date: 1996/02

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