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Mould-associated asthma.

Author(s) : FUNG F., YOUNG C.

Summary

There is increasing evidence that mould allergens, especially Alternaria and Cladosporium, are implicated in contributing to allergic reaction, rhinitis, and asthma. Situations leading to the exacerbation of asthma in three individuals were investigated. Industrial hygiene studies with bioaerosol testing revealed the presence of several mould allergens. Based on the medical evaluation and testing results, it was concluded that mould allergen was associated with the respiratory reaction. Post-remedial bioaerosol sampling results revealed background fungal levels and the inciting allergen was no longer present. Practically, several factors should be considered prior to concluding an association between exposure and illness. First, the person's symptoms and signs should be consistent with a medical diagnosis. Second, there should be either in vitro or in vivo evidence of exposure. Third, environmental assessment should reveal evidence of plausible biological exposure. Fourth, there should be substantial improvement or even resolution of the illness after appropriate remediation of the health hazard.

Details

  • Original title: Mould-associated asthma.
  • Record ID : 2005-1450
  • Languages: English
  • Source: IAQ 2001. Moisture, microbes and health effects: indoor air quality and moisture in buildings [CD-ROM].
  • Publication date: 2002

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