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Regulation of hepatic intracellular pH at hypothermia: a comparison of hibernating and non-hibernating species using 31P NMR spectroscopy.

Author(s) : FULLER B. J., BUSZA A. L., LOCKETT C. J., SIMPKIN S., WANG L. H., GREEN C. J.

Type of article: Article

Summary

Liver metabolism at hypotermia was studied in vitro in livers from normal rat and hibernating squirrels using 31P NMR spectroscopy. During continuous perfusion at 6-8 deg C with oxygenated buffer, livers from both species maintained levels of high-energy phosphorylated adenylates, while intrahepatic pH was shifted to values predicted from the "alpha-stat" hypothesis. No specific differences in metabolism were detected between the homeotherm and hibernating species.

Details

  • Original title: Regulation of hepatic intracellular pH at hypothermia: a comparison of hibernating and non-hibernating species using 31P NMR spectroscopy.
  • Record ID : 1996-3740
  • Languages: English
  • Source: Cryo-Letters - vol. 16 - n. 6
  • Publication date: 1995/11
  • Document available for consultation in the library of the IIR headquarters only.

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