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Selective freezing of target biological tissues after injection of solutions with specific thermal properties.

Author(s) : YU T. H., LIU J., ZHOU Y. X.

Type of article: Article

Summary

Cryosurgery is a minimally invasive surgical technique that employs the destructive effect of freezing to eradicate undesirable tissues. This article describes a flexible method to control the size and shape of the iceball by injecting solutions with specific thermal properties into the target tissues, to enhance freezing damage to the diseased tissues while preserving the normal tissues from injury. The experimental results demonstrate that the localized injection of an appropriate solution could enhance the tumour-killing effect without altering the freezing conditions. The study also suggests the potential value of combining cryosurgery with other therapeutic methods, such as electrical, chemical, and thermal treatments, to develop new clinical modalities in the near future.

Details

  • Original title: Selective freezing of target biological tissues after injection of solutions with specific thermal properties.
  • Record ID : 2006-0466
  • Languages: English
  • Source: Cryobiology - vol. 50 - n. 2
  • Publication date: 2005/04

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