IIR document

The effects of high intensity interval training combined with the whole body cryostimulation on brain-derived neurotrophic factor and tryptophan metabolism.

Summary

The aim of this study was to verify if combination of high intensity interval training and coldness modify kynurenine and amino acid profiles and whether exerkines induced by muscle contractions regulate potential changes.
Twenty-two subjects were randomly divided in 2 groups: performed 6 sessions of HIIT or maintain the same daily habits and additionally underwent 10 sessions whole-body-cryostimulation (at -110°C, for 3 minutes each) (CRYO-HIIT). Blood was collected at baseline and 24h post intervention. The concentration of selected exerkines were assessed using enzyme immunoassay method, whereas tryptophan metabolites were analysed on high performance liquid chromatography combined with the tandem mass spectrometry. Obtained results showed that HIIT significantly increased the concentration of BDNF compared to CRYO-HIIT. Both procedures affected tryptophan metabolite expressed in significant ratio kynurenine to kynurenine acid. Also, phenylalanine to tyrosine altered significant in HIIT group. These data suggest that both procedures could have different effect and should be accurately applied.

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Details

  • Original title: The effects of high intensity interval training combined with the whole body cryostimulation on brain-derived neurotrophic factor and tryptophan metabolism.
  • Record ID : 30031565
  • Languages: English
  • Subject: Technology
  • Source: Proceedings of the 26th IIR International Congress of Refrigeration: Paris , France, August 21-25, 2023.
  • Publication date: 2023/08/21
  • DOI: http://dx.doi.org/10.18462/iir.icr.2023.0646

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