Summary
The glass transition temperature of lyoprotectants for biomaterials is important in the lyoprotectant selection, freeze-drying process design and storage condition determination. In this study, trehalose, lactose, maltose, sucrose, glucose and bovine serum albumin were adopted to be lyoprotectants. Differential scanning calorimetry was employed to measure the glass transition temperature of suspension and freeze-dried samples. The factors influencing the glass transition temperature of suspension and freeze-dried samples were investigated.
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Details
- Original title: [In Chinese. / En chinois.]
- Record ID : 2009-0411
- Languages: Chinese
- Source: Journal of Refrigeration - vol. 29 - n. 123
- Publication date: 2008/10
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Indexing
- Themes: Freeze-drying in biology and medicine
- Keywords: Glass transition; Freeze-drying; Calorimetry; Biological material; Material
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Thermal analysis of lyoprotectants for biomater...
- Author(s) : ZHOU X. L., TAO H., ZHANG S. Z., et al.
- Date : 2007/08/21
- Languages : English
- Source: ICR 2007. Refrigeration Creates the Future. Proceedings of the 22nd IIR International Congress of Refrigeration.
- Formats : PDF
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Study on preparation of proliposomes by freeze-...
- Author(s) : ZUO J. G., HUA Z. H.
- Date : 2007/08/21
- Languages : English
- Source: ICR 2007. Refrigeration Creates the Future. Proceedings of the 22nd IIR International Congress of Refrigeration.
- Formats : PDF
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Research on freeze-drying of human bone mesench...
- Author(s) : YANG P., CHENG Q., WANG X., et al.
- Date : 2005
- Languages : Chinese
- Source: Journal of Refrigeration - n. 1
- Formats : PDF
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Stabilizing an enzyme by freeze-drying: the inf...
- Author(s) : SPIELES G., WESTIN K. J. E., HESCHEL I., RAU G.
- Date : 1995/08/20
- Languages : English
- Source: For a Better Quality of Life. 19th International Congress of Refrigeration.
- Formats : PDF
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PHASE TRANSITIONS IN FROZEN ANTIBIOTIC SOLUTIONS.
- Author(s) : DELUCA P. P.
- Date : 1985/05/20
- Languages : English
- Source: Fundamentals and Applications of Freeze-Drying to Biological Materials, Drugs and Foodstuffs.
- Formats : PDF
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