ShareAN ANALYTICAL METHOD TO EVALUATE COOLING RATES DURING CRYOPRESERVATION PROTOCOLS FOR ORGANS.
Author(s) : RUBINSKY B., CRAVALHO E. G.
Type of article: Article
Summary
A SIMPLE, GRAPHICAL PROCEDURE HAS BEEN ESTABLISHED TO ESTIMATE THE COOLING RATES AT A SPECIFIED LOCATION AND TEMPERATURE IN A BIOLOGICAL MEDIUM FROZEN BY IMPOSING A CONSTANT COOLING RATE AT THE OUTER SURFACE. THE GRAPHICAL PROCEDURE ALSO FACILITATES THE DETERMINATION OF THE OUTER SURFACE TEMPERATURE AT THE INSTANT A GIVEN TEMPERATURE HAS BEEN ATTAINED IN A SPECIFIC LOCATION. THE RESULTS OBTAINED THROUGH A NUMERICAL STUDY USING FINITE ELEMENTS CAN BE APPLIED TO BIOLOGICAL MEDIA WITH VARIOUS CHEMICAL COMPOSITIONS INCLUDING DIFFERENT CONCENTRATIONS OF CRYOPROTECTIVE AGENTS.
Details
- Original title: AN ANALYTICAL METHOD TO EVALUATE COOLING RATES DURING CRYOPRESERVATION PROTOCOLS FOR ORGANS.
- Record ID : 1985-0823
- Languages: English
- Source: Cryobiology - vol. 21 - n. 3
- Publication date: 1984
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