An immunohistochemical study of keloids and keloidal fibroblasts and effects of cryotherapy on proliferation, synthetic activity and immunophenotype of human keloidal and normal fibroblasts in vitro.

Immunhistochemische Untersuchungen an keloiden und keloidalen Fibroblasten und der Einfluss der Kryotherapie auf Proliferation, synthetische Aktivität und Immunphänotyp humaner keloidaler und normaler Fibroblasten in vitro.

Author(s) : DALKOWSKI A.

Type of monograph: Doctoral thesis

Summary

This thesis presented for the degree of Doctor at the Department of Dermatology, at the University Medical Center Benjamin Franklin, of the free University of Berlin: investigates the differences between keloids and unaffected skin in vivo using immunohistochemistry; compares cell proliferation, synthesis of extracellular matrix proteins and immunophenotype between cultured keloidal and normal fibroblasts in vitro; studies the influence of cryotherapy on cultured keloidal and normal fibroblasts in vitro with regard to proliferation, synthetic activity and immunophenotype using a model of controlled cryoapplication on cell cultures developed in the University's laboratory. A long summary in English (4 pages) goes with the thesis. During the Sydney Congress of the IIR, September 19-24, 1999, the author was awarded the IIR Alexis Carrel Prize to Young Researchers for this work.

Details

  • Original title: Immunhistochemische Untersuchungen an keloiden und keloidalen Fibroblasten und der Einfluss der Kryotherapie auf Proliferation, synthetische Aktivität und Immunphänotyp humaner keloidaler und normaler Fibroblasten in vitro.
  • Record ID : 2000-0523
  • Languages: German
  • Publication: Papyrus-druck - Germany/Germany
  • Publication date: 1997/12/12
  • Source: Source: 156 p. (14.7 x 20.7); fig.; tabl.
  • Document available for consultation in the library of the IIR headquarters only.