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Antifreeze glycoproteins from Antarctic notothenioid fishes fail to protect the rat cardiac explant during hypothermic and freezing preservation.

Author(s) : WANG T., ZHU Q., YANG X., LAYNE J. R. Jr, DEVRIES A. L.

Type of article: Article

Summary

The study investigated whether AFGPs (antifreeze glycoproteins) could serve as cryoprotectants for the isolated rat heart under three different storage conditions. Notothenioid fish AFGPs not only fail to enhance storage of the isolated rat heart preparation at hypothermic temperatures, but cause increased damage under freezing conditions regardless of AFGP concentration.

Details

  • Original title: Antifreeze glycoproteins from Antarctic notothenioid fishes fail to protect the rat cardiac explant during hypothermic and freezing preservation.
  • Record ID : 1995-1218
  • Languages: English
  • Source: Cryobiology - vol. 31 - n. 2
  • Publication date: 1994/04

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