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Cryopreservation of arteries.

Author(s) : BATESON E. A. J., PEGG D. E.

Type of article: Article

Summary

The paper characterises the rabbit common carotid artery as an animal model for human small elastic arteries and reports the results of storage at 4 deg C and cryopreservation using a standard technique with DMSO, slow cooling and rapid warming. Some deterioration of smooth muscle function was observed after 5 days at 4 deg C. Tissue that was cryopreserved in 1.2 or 1.8 mol/l DMSO showed undiminished sensitivity to the agonists studied and retained about 40% of its initial smooth muscle contractility and about 60% of its capacity to relax in response to endothelium-derived relaxation factor.

Details

  • Original title: Cryopreservation of arteries.
  • Record ID : 1994-2559
  • Languages: English
  • Source: Cryo-Letters - vol. 15 - n. 1
  • Publication date: 1994/01
  • Document available for consultation in the library of the IIR headquarters only.

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