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Cryopreservation of rabbit kidney.

Author(s) : KIRPATOVSKIJ V. I., KUDRIAVTSEV Ju. V., BUROV V. N.

Type of article: Article

Summary

Kidneys of 21 rabbits were preserved at -20 or -70 deg C under protection of 15% DMSO. The blood flow was not restored after transplantation of kidneys preserved at -70 deg C, due to the blockage of microcirculation, while a satisfactory blood supply with inadequate perfusion sites was noted after freezing to -20 deg C. The histologic examination 1 hour after transplantation demonstrated mild damage in glomerula and tubules. The changes were more minor in experiments with alpha-tocopherol added to the perfusate. It was concluded that the renal microcirculation bed is highly sensitive to cold and this may be responsible for the loss of viability of cryopreserved kidney after transplantation.

Details

  • Original title: Cryopreservation of rabbit kidney.
  • Record ID : 1993-1127
  • Languages: English
  • Source: Probl. Cryobiol. - n. 1
  • Publication date: 1992
  • Document available for consultation in the library of the IIR headquarters only.

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